Police are asking witnesses to come forward after a fatal crash in Lake Macquarie overnight.
Just after 2am, police believe a Hyundai Getz collided with a Holden Commodore on the Pacific Highway near Cams Wharf.
Both cars were travelling in different directions.
One of the drivers, a 38-year-old female was killed at the scene and a report is now being prepared for the coroner.
The other driver, a 49-year-old male was taken to the John Hunter Hospital with serious injuries.
Anyone with information is urged to call Police or contact Crime Stoppers on 1800 333 000.